To understand Pain and how Cannabis can help and treat pain, lets first take a look at what pain is
Pain signals journey to the brain with the aid of one of three fundamental pathways, each of which creates distinct pain sensations in the nervous system:
- Somatic pain
Somatic pain is the sensation most of the people believe when they consider pain: a message despatched by bodily receptors each time injury occurs. Somatic pain alerts travel to the brain via peripheral nerves, and are generally experienced as a steady, lasting pain.
- Visceral pain
Visceral pain takes place when tissues or organs within the abdominal cavity become stretched because of sickness or damage. In such cases, pain signals issue from a particular class of receptors located inside the gut itself, producing unpleasant emotions of feelings of deep pressure inside the stomach.
- Neuropathic pain
Neuropathic pain takes place when nerves themselves are sustain injuries. it is regularly experienced as an unpleasant burning sensation. This type of pain does not typically listen to narcotic painkillers, which are known to relief many other varieties of pain.
Many studies have demonstrated that cannabis related products suppress pain via distinct mechanisms.
Medical Marijuana has proven its anti-pain usage after administration in basic experiments on pain. Peripheral nerves that detect pain sensations contain receptors for cannabinoids. Cannabinoids such as Cannabis administered by way of smoking it, or usage of the pill form, seems to block peripheral nerve pain in conducted experiments.
To understand Marijuana as a pain medication, we first have to take a look at other more traditional sources of pain management, for simplicity’s sake, lets quickly take a look at the following three;
Hydromorphone which Is referred to as dihydromorphinone is branded and sold under the name Dilaudid, and other brands as well, it is of opioid nature.
In scientific terms, hydromorphone is to morphine as hydrocodone is to codeine.
In medical terminology, it is an opioid analgesic, and in legal terms, it is a narcotic.
Hydromorphone is typically used in the health clinics, hospitals, and emergency rooms, usually through the administration of (IV) format. Sublingual administration of the drug, “by waiting until the pill is dissolved as it’s placed under your tongue”, is commonly the way it is administered in medical facilities.
A pill shape of marijuana gives extra pain alleviation than when someone smokes it, some studies have found.
The study was conducted with the aid of researchers at Columbia University located at New York State and was publicized in the magazine called “Neuropsychopharmacology”.
The pill, known as Dronabinol, incorporates the active factor of marijuana – tetrahydrocannabinol, also publically known as THC – This pill has already been authorized to treat chemotherapy and AIDS patients who suffer from nausea and vomiting conditions.
The scientists stated:
“latest research has demonstrated the healing capability of cannabinoids to treat ache, yet none have compared the analgesic effectiveness of smoked marijuana to orally administered tetrahydrocannabinol (THC; dronabinol).”
A study which was conducted involved 30 members (15 males and 15 female participants) who had previously been marijuana smokers. The researchers itself which were led and coordinated by Ziva Cooper and Margaret Haney set out to compare subjects’ daily pain response and it’s relation to Cannabis.
The study volunteers were requested to either to smoke marijuana, take oral Dronabinol, or were given a placebo for good measures. The volunteers then took part of an experiment called a “cold pressor test” where they immersed their hand in a bath of extremely cold water (4 degrees Celsius) which lasted up to two minutes.
So how much time did it take them to report pain (sensitivity factor) and cast off their hand from the water (tolerance factor) were documented for good measure.
Based on this study, resulted were obtained that in compared, marijuana to Dronabinol to the placebo;
The researchers said that
“The magnitude in pain sensitivity and pain tolerance did not differ much between marijuana and dronabinol, however they noted taht dronabinol produced analgesia that lasted for an extended period.”
A previously conducted clinical study confirmed that an oral pill of THC tended to make the experience of pain more bearable.
Another more recent study suggests that 93% of patients prefer cannabis Over Opioids For coping with pain.
A new study investigated what patients themselves prefer, whether it be an opioid of medical marijuana.
The researchers determined that a lot more patients prefer medical marijuana to commonly distributed drugs such as Morphine and Codeine. And unlike in previous times, many trust it is simply a powerful pain relief solution.
“This study concludes that medical cannabis patients document efficiently the usage of cannabis along side or as an alternative for opioid based pain medicinal drugs,” the group reported inside the magazine cannabis and Cannabinoid studies.
patients in this study who were administered cannabis and opioids documented that they were able to use much fewer opioids and that marijuana presents less undesirable consequences than opioids.
Research conducted at Kent state university and California Berkeley University their emailed participants a survey and asked them about their pain, and their opioid and Cannabis usage.
Out of the 2,810 individuals who were presently using cannabis, 828 had used opioids in the closing 6 months to control their pain.
Of that group, “97 percent of the group strongly agreed that they’re able to decrease the quantity of opioids they consume while they also use cannabis”.
In addition, 89 percent ‘strongly agreed’ that taking opioids produces unwanted side consequences consisting but not limited to constipation and nausea, as stated by the researchers.
The study co-coordinators also discovered that “81 percent ‘strongly agreed’ that taking cannabis alone become more effective at treating their medical condition than taking cannabis with opioids as a combo.
If given the selection and left to the individual to choose, many individuals favor the use of cannabis than opioids. This level of inclination to marijuana can be seen in the graph bellow.
Additional studies showed that that sufferers with chronic neuropathic pain, smoking marijuana or eating it in pill form, reduced their signs of pain, helped them ease their anger issues and helped them sleep better.
Cancer, Back pain, multiple sclerosis, AIDS patients, Migraines and many more diagnosed patients are turning to Marijuana as a source for pain relief. Marijuana is becoming more and more acceptable as a mainstream pain solution, not only in small communities but now all across various nations.
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